Pub. Date : 2006 Sep 12
PMID : 16940356
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recently, it was reported that, in contrast to previous observations, the affinity of EF-G was much weaker for GTP than for GDP and that ribosome-catalyzed GDP-GTP exchange would be required for translocation [Zavialov AV, Hauryliuk VV, Ehrenberg M (2005) J Biol 4:9]. | Guanosine Diphosphate | G elongation factor mitochondrial 1 | Homo sapiens |
| 2 | We have reinvestigated GTP/GDP binding and show that EF-G binds GTP and GDP with affinities in the 20 to 40 microM range (37 degrees C), in accordance with earlier reports. | Guanosine Diphosphate | G elongation factor mitochondrial 1 | Homo sapiens |
| 3 | We have reinvestigated GTP/GDP binding and show that EF-G binds GTP and GDP with affinities in the 20 to 40 microM range (37 degrees C), in accordance with earlier reports. | Guanosine Diphosphate | G elongation factor mitochondrial 1 | Homo sapiens |
| 4 | Furthermore, GDP exchange, which is extremely rapid on unbound EF-G, is retarded, rather than accelerated, on the ribosome, which, therefore, is not a nucleotide-exchange factor for EF-G. | Guanosine Diphosphate | G elongation factor mitochondrial 1 | Homo sapiens |