Title : Relative suppression of the sodium-dependent Vitamin C transport in mouse versus human lens epithelial cells.

Pub. Date : 2006 Dec

PMID : 16933033






1 Functional Relationships(s)
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1 Incubation of cells with 6-deoxy-6-fluoro-ascorbic (F-ASA), i.e. a probe specific for the sodium-dependent Vitamin C uptake (SVCT2), revealed a 10-fold uptake suppression into mouse 17EM15 relative to human HLE-B3 and JAR choriocarcinoma cells (a control), that could be overcome by overexpressing hSVCT2 using two different promoter constructs. 6-deoxy-6-fluoro-ascorbic solute carrier family 23 member 2 Homo sapiens