Title : Apoptosis induced by acrylamide in SH-SY5Y cells.

Pub. Date : 2007 Apr

PMID : 16932918






2 Functional Relationships(s)
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1 The caspase-3 activity and cell population in sub-G(1) phase were elevated and peaked on exposure to 3 mM acrylamide, while both were less so at higher dose (4 and 5 mM). Acrylamide caspase 3 Homo sapiens
2 Thus, although mechanisms other than caspase-dependent apoptosis may be involved, apoptotic process seems to take place in the genesis of toxicity of acrylamide in SH-SY5Y cells through ERK pathway and activation of caspase-3. Acrylamide caspase 3 Homo sapiens