Title : Phosphatase PTEN is inactivated in bovine aortic endothelial cells exposed to cyclic strain.

Pub. Date : 2007 Feb 1

PMID : 16927376






3 Functional Relationships(s)
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1 The activity of phospho-PTEN (n = 4) and phospho-CK2 (n = 4) increased in a time-dependent fashion, reaching maximal activity by 10 min of CS stimulation. Cesium phosphatase and tensin homolog Bos taurus
2 Furthermore, CS increased PIP3 immunoreactivity in a time-dependent manner, reaching maximal activity after 60 min of CS stimulation, and these effects were affected by transfection of EC with dominant negative PTEN plasmids. Cesium phosphatase and tensin homolog Bos taurus
3 Inhibition of PTEN activity had no effect on CS-mediated cell proliferation but inhibited CS-mediated suppression of apoptosis. Cesium phosphatase and tensin homolog Bos taurus