Title : Drugs elevating extracellular adenosine administered in vivo induce serum colony-stimulating activity and interleukin-6 in mice.

Pub. Date : 2007

PMID : 16925466






3 Functional Relationships(s)
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1 Our previous studies have shown that the combined administration of drugs elevating extracellular adenosine, i.e. dipyridamole (DP) and adenosine monophosphate (AMP), enhances murine hematopoiesis and potentiates the action of granulocyte colony-stimulating factor (G-CSF). Dipyridamole colony stimulating factor 3 (granulocyte) Mus musculus
2 Our previous studies have shown that the combined administration of drugs elevating extracellular adenosine, i.e. dipyridamole (DP) and adenosine monophosphate (AMP), enhances murine hematopoiesis and potentiates the action of granulocyte colony-stimulating factor (G-CSF). Dipyridamole colony stimulating factor 3 (granulocyte) Mus musculus
3 Our results show that the effects of DP+AMP are indirect, mediated through the induction of some cytokine(s) and/or growth factor(s) and that extracellular adenosine can act in cooperation with G-CSF. Dipyridamole colony stimulating factor 3 (granulocyte) Mus musculus