Title : ATP stimulates mouse embryonic stem cell proliferation via protein kinase C, phosphatidylinositol 3-kinase/Akt, and mitogen-activated protein kinase signaling pathways.

Pub. Date : 2006 Dec

PMID : 16916926






2 Functional Relationships(s)
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Protein Name
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1 ATP phosphorylated Akt and p44/42 mitogen-activated protein kinases (MAPKs) in a time-dependent manner, and either suramin or reactive blue 2 (RB2) blocked the ATP-induced phosphorylation of Akt. Adenosine Triphosphate mitogen-activated protein kinase 3 Mus musculus
2 The ATP-induced increase in [(3)H]thymidine incorporation was inhibited by wortmannin, the Akt inhibitor, and the MAPK kinase inhibitor (PD 98059). Adenosine Triphosphate mitogen-activated protein kinase 3 Mus musculus