Pub. Date : 2006 Nov 25
PMID : 16916529
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Within this domain, highly conserved lysine and arginine residues significantly contributed to Nef"s membrane association and localization. | Lysine | S100 calcium binding protein B | Homo sapiens |
| 2 | Importantly, two lysines at positions 4 and 7 were not essential for the overall membrane association but critically contributed to Nef"s incorporation into lipid raft domains. | Lysine | S100 calcium binding protein B | Homo sapiens |
| 3 | Cell surface receptor downmodulation was largely unaffected by mutations of all N-terminal basic residues, while the association of Nef with Pak2 kinase activity and its ability to augment virion infectivity correlated with its lysine-mediated raft incorporation. | Lysine | S100 calcium binding protein B | Homo sapiens |