Title : DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid.

Pub. Date : 2006 Aug

PMID : 16913876






2 Functional Relationships(s)
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1 The DAF-12 ligand has been predicted to be a sterol that is metabolized by DAF-9, a cytochrome P450. Sterols Nuclear hormone receptor family member daf-12 Caenorhabditis elegans
2 Here we chemically characterize purified lipophilic nematode extracts and show that the ligand for DAF-12 contains a carboxyl moiety and is likely to be derived from a sterol. Sterols Nuclear hormone receptor family member daf-12 Caenorhabditis elegans