Title : Site-specific mutagenesis of the histidine precursor of diphthamide in the human elongation factor-2 gene confers resistance to diphtheria toxin.

Pub. Date : 2006 Oct 10

PMID : 16901746






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Site-specific mutagenesis of the histidine precursor of diphthamide in the human elongation factor-2 gene confers resistance to diphtheria toxin. Histidine eukaryotic translation elongation factor 2 Homo sapiens
2 Protein synthesis elongation factor 2 (EF-2) from eukaryotes contains a conserved post-translationally modified histidine residue known as diphthamide. Histidine eukaryotic translation elongation factor 2 Homo sapiens
3 Protein synthesis elongation factor 2 (EF-2) from eukaryotes contains a conserved post-translationally modified histidine residue known as diphthamide. Histidine eukaryotic translation elongation factor 2 Homo sapiens
4 Using site-specific mutagenesis of the histidine precursor of diphthamide, the histidine residue of codon 715 in human EF-2 cDNA was substituted with one of four amino acid residue codons: leucine, methionine, asparagine or glutamine. Histidine eukaryotic translation elongation factor 2 Homo sapiens
5 Using site-specific mutagenesis of the histidine precursor of diphthamide, the histidine residue of codon 715 in human EF-2 cDNA was substituted with one of four amino acid residue codons: leucine, methionine, asparagine or glutamine. Histidine eukaryotic translation elongation factor 2 Homo sapiens