Pub. Date : 1990 Mar 1
PMID : 1689750
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Antiphosphotyrosine immunoblots were used to characterize tyrosine phosphorylated proteins after stimulation of the human TCR. | Tyrosine | T cell receptor beta variable 20/OR9-2 (non-functional) | Homo sapiens |
| 2 | Increased tyrosine phosphorylation was evident on at least 12 substrates within 2 min after ligation of the TCR with mAb. | Tyrosine | T cell receptor beta variable 20/OR9-2 (non-functional) | Homo sapiens |
| 3 | When the TCR complex was cross-linked together with the CD4 receptor by heteroconjugate anti-CD3/CD4 mAb, an increased magnitude of tyrosine phosphorylation occurred, although no new substrates could be detected. | Tyrosine | T cell receptor beta variable 20/OR9-2 (non-functional) | Homo sapiens |
| 4 | Thus, these findings show that increased tyrosine phosphorylation is the earliest yet detected signal observed after ligation of the TCR complex, and furthermore suggest that tyrosine phosphorylation might link the TCR to the phosphatidylinositolbisphosphate hydrolysis signaling pathway. | Tyrosine | T cell receptor beta variable 20/OR9-2 (non-functional) | Homo sapiens |
| 5 | Thus, these findings show that increased tyrosine phosphorylation is the earliest yet detected signal observed after ligation of the TCR complex, and furthermore suggest that tyrosine phosphorylation might link the TCR to the phosphatidylinositolbisphosphate hydrolysis signaling pathway. | Tyrosine | T cell receptor beta variable 20/OR9-2 (non-functional) | Homo sapiens |
| 6 | Thus, these findings show that increased tyrosine phosphorylation is the earliest yet detected signal observed after ligation of the TCR complex, and furthermore suggest that tyrosine phosphorylation might link the TCR to the phosphatidylinositolbisphosphate hydrolysis signaling pathway. | Tyrosine | T cell receptor beta variable 20/OR9-2 (non-functional) | Homo sapiens |
| 7 | Thus, these findings show that increased tyrosine phosphorylation is the earliest yet detected signal observed after ligation of the TCR complex, and furthermore suggest that tyrosine phosphorylation might link the TCR to the phosphatidylinositolbisphosphate hydrolysis signaling pathway. | Tyrosine | T cell receptor beta variable 20/OR9-2 (non-functional) | Homo sapiens |