Pub. Date : 1990 Feb
PMID : 1689684
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role of secretin and cholecystokinin in oleic acid-stimulated pancreatic secretion in rats. | Oleic Acid | cholecystokinin | Rattus norvegicus |
| 2 | We investigated the possible role of endogenous secretin and cholecystokinin (CCK) on oleic acid-stimulated pancreatic exocrine secretion in anesthetized rats. | Oleic Acid | cholecystokinin | Rattus norvegicus |
| 3 | Plasma secretin and CCK concentrations also elevated significantly in response to oleic acid, in a dose-related manner (r = 0.721 and 0.546, respectively) (P less than 0.001). | Oleic Acid | cholecystokinin | Rattus norvegicus |
| 4 | There were statistically significant correlations between plasma secretin concentrations and bicarbonate outputs, and between plasma CCK concentrations and amylase outputs in response to oleic acid (P less than 0.01). | Oleic Acid | cholecystokinin | Rattus norvegicus |
| 5 | Potent CCK antagonist, CR 1409 (5 mg/kg.hr) administered intravenously suppressed completely increase in amylase output induced by oleic acid, and partially in juice volume and bicarbonate output. | Oleic Acid | cholecystokinin | Rattus norvegicus |
| 6 | It is concluded that both endogenous secretin and CCK play important roles on oleic acid-induced pancreatic secretion in rats. | Oleic Acid | cholecystokinin | Rattus norvegicus |