Title : 15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis.

Pub. Date : 2006 Jul

PMID : 16891469






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 DR5/Fc chimera protein, zVAD-fmk pancaspase inhibitor, and caspase-8 inhibitor efficiently blocked the activation of these apoptotic signal mediators and the induction of apoptotic cell death enhanced by cotreatment with 15d-PGJ(2) and TRAIL. 15d-pgj caspase 8 Homo sapiens