Pub. Date : 2006 Sep 29
PMID : 16891316
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Based on this, we propose that a pathway composed of ATR, PML, Chk2, and p53 plays a role in ATO-mediated apoptosis, a notion that is consistent with the observation that Chk2 is genetically intact and mutations in the p53 gene are extremely rare in APL. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
2 | Based on this, we propose that a pathway composed of ATR, PML, Chk2, and p53 plays a role in ATO-mediated apoptosis, a notion that is consistent with the observation that Chk2 is genetically intact and mutations in the p53 gene are extremely rare in APL. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |