Title : Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.

Pub. Date : 2006 Aug

PMID : 16886063






1 Functional Relationships(s)
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1 Finally, this disease prevention occurred in Treg-deficient NOD.B7-1/B7-2 double-knockout mice, suggesting that the effect of the CTLA-4 agonist directly attenuates autoreactive T cell activation, not Treg activation. treg cytotoxic T-lymphocyte-associated protein 4 Mus musculus