Title : Gonadal steroid regulation of substance P (SP) and SP-encoding messenger ribonucleic acids in the rat anterior pituitary and hypothalamus.

Pub. Date : 1990 Jan

PMID : 1688409






2 Functional Relationships(s)
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1 Ovariectomized rats treated for 10 days with estradiol benzoate showed a 50% decrease in AP SP and a 90% decrease in AP beta- and gamma-PPT mRNAs compared to ovariectomized oil-treated controls. estradiol 3-benzoate tachykinin, precursor 1 Rattus norvegicus
2 Estradiol benzoate replacement had no effect on SP levels in the isolated ME, but did cause a 50% increase in alpha-, beta-, and gamma PPT mRNAs in the hypothalamus. estradiol 3-benzoate tachykinin, precursor 1 Rattus norvegicus