Pub. Date : 2006 Nov 15
PMID : 16876345
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | It has been previously reported that beta-cyclodextrin (beta-CD) enhances the oral absorption of the pentavalent antimony (Sb) drug, meglumine antimoniate (MA). | Antimony | beta-carotene oxygenase 1 | Mus musculus |
2 | When MA solution was heated for 48 h at 55 degrees C to mimic the conditions used to prepare MA/beta-CD, MA was found to suffer dissociation, from high molecular weight Sb complexes into species of lower molecular weight. | Antimony | beta-carotene oxygenase 1 | Mus musculus |
3 | In vitro skin permeation experiments using MA and MA/beta-CD indicated a two-fold increase in the Sb flux for MA/beta-CD. | Antimony | beta-carotene oxygenase 1 | Mus musculus |
4 | In vitro skin permeation experiments using MA and MA/beta-CD indicated a two-fold increase in the Sb flux for MA/beta-CD. | Antimony | beta-carotene oxygenase 1 | Mus musculus |