Title : Tethered yohimbine analogs as selective human alpha2C-adrenergic receptor ligands.

Pub. Date : 2006 Nov

PMID : 16873606






3 Functional Relationships(s)
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1 Tethered yohimbine analogs as selective human alpha2C-adrenergic receptor ligands. Yohimbine adrenoceptor alpha 2C Homo sapiens
2 In an earlier report, we demonstrated that dimeric yohimbine analogs containing methylene and methylene-diglycine tethers were highly selective human alpha(2C)-AR ligands. Yohimbine adrenoceptor alpha 2C Homo sapiens
3 The profiles of pharmacological activity for the yohimbine analogs on the three human alpha(2)-AR subtypes expressed in Chinese hamster ovary cells were examined using receptor binding and cAMP inhibition assays. Yohimbine adrenoceptor alpha 2C Homo sapiens