Title : Role of the Arabidopsis DNA glycosylase/lyase ROS1 in active DNA demethylation.

Pub. Date : 2006 Aug 1

PMID : 16864782






2 Functional Relationships(s)
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1 Our data suggest that the DNA glycosylase activity of ROS1 removes 5-methylcytosine from the DNA backbone and then its lyase activity cleaves the DNA backbone at the site of 5-methylcytosine removal by successive beta- and delta-elimination reactions. 5-Methylcytosine demeter-like 1 Arabidopsis thaliana
2 Our data suggest that the DNA glycosylase activity of ROS1 removes 5-methylcytosine from the DNA backbone and then its lyase activity cleaves the DNA backbone at the site of 5-methylcytosine removal by successive beta- and delta-elimination reactions. 5-Methylcytosine demeter-like 1 Arabidopsis thaliana