Title : HPRT gene expression differs in mutants derived from normal and Fanconi anemia cells: analysis of spontaneous and psoralen-photoinduced mutants.

Pub. Date : 1991 Nov

PMID : 1685031






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We previously reported that after photoaddition of psoralen derivatives the frequency of HPRT- mutants was significantly lower in FA than in normal human lymphoblasts. Ficusin hypoxanthine phosphoribosyltransferase 1 Homo sapiens
2 In normal cells, the minority of spontaneous (31%) and psoralen-induced mutants (0% and 14% according to treatment) arise from mutations that alter the HPRT gene transcription. Ficusin hypoxanthine phosphoribosyltransferase 1 Homo sapiens