Title : Nuclear type II [3H]estradiol binding site ligands: inhibition of ER-positive and ER-negative cell proliferation and c-Myc and cyclin D1 gene expression.

Pub. Date : 2006 Oct

PMID : 16839579






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both ZN-1 and ZN-2 blocked estradiol stimulation of c-Myc and cyclin D1 gene expression in MCF-7 cells, two events that are clearly coupled to cell cycle progression. Estradiol cyclin D1 Homo sapiens