Title : Anticonvulsants for poisoning by the organophosphorus compound soman: pharmacological mechanisms.

Pub. Date : 1991 Fall

PMID : 1683477






3 Functional Relationships(s)
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1 We have examined the possibility that diazepam may exert some of its anticonvulsant effects through cholinergic mechanisms and found that a reduced release of ACh into synapses after diazepam and atropine treatment may account for diazepam"s anticonvulsant activity against soman. Diazepam acyl-CoA thioesterase 12 Rattus norvegicus
2 We have examined the possibility that diazepam may exert some of its anticonvulsant effects through cholinergic mechanisms and found that a reduced release of ACh into synapses after diazepam and atropine treatment may account for diazepam"s anticonvulsant activity against soman. Diazepam acyl-CoA thioesterase 12 Rattus norvegicus
3 We have examined the possibility that diazepam may exert some of its anticonvulsant effects through cholinergic mechanisms and found that a reduced release of ACh into synapses after diazepam and atropine treatment may account for diazepam"s anticonvulsant activity against soman. Diazepam acyl-CoA thioesterase 12 Rattus norvegicus