Title : Pharmacokinetics and bioequivalence evaluation of risperidone in healthy male subjects with different CYP2D6 genotypes.

Pub. Date : 2006 Jun

PMID : 16833023






2 Functional Relationships(s)
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1 The CYP2D6*10 allele particularly was associated with higher serum concentrations of risperidone and the risperidone/9-OH-risperidone ratio compared with the CYP2D6*1 allele. Paliperidone Palmitate cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 Furthermore, the pharmacokinetic parameters of risperidone and the risperidone/9-OH-risperidone ratio are highly dependent on the CYP2D6 genotypes. Paliperidone Palmitate cytochrome P450 family 2 subfamily D member 6 Homo sapiens