Title : Proteasome-independent down-regulation of estrogen receptor-alpha (ERalpha) in breast cancer cells treated with 4,4'-dihydroxy-trans-stilbene.

Pub. Date : 2006 Aug 28

PMID : 16822479






1 Functional Relationships(s)
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1 Here, we present data to show that both 4-OH and 4"-OH are critical for the ability of 4,4"-DHS to induce down-regulation of ERalpha and suggest that 4,4"-DHS provides a useful scaffold for development of novel ERalpha antagonists. 4-oh estrogen receptor 1 Homo sapiens