Pub. Date : 2006 Jun 30
PMID : 16819278
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Heterogeneous nuclear ribonuclear protein C is increased in the celecoxib-induced growth inhibition of human oral squamous cell carcinoma. | Celecoxib | heterogeneous nuclear ribonucleoprotein C | Homo sapiens |
| 2 | Using proteomics, the 10- to 20-fold increase of heterogeneous nuclear ribonuclear protein C (hnRNP C), which has been suggested to be related with the translation of p(27) mRNA, was observed in celecoxib-treated YD-10(B) cells. | Celecoxib | heterogeneous nuclear ribonucleoprotein C | Homo sapiens |
| 3 | Using proteomics, the 10- to 20-fold increase of heterogeneous nuclear ribonuclear protein C (hnRNP C), which has been suggested to be related with the translation of p(27) mRNA, was observed in celecoxib-treated YD-10(B) cells. | Celecoxib | heterogeneous nuclear ribonucleoprotein C | Homo sapiens |
| 4 | In summary, celecoxib has a potential to induce the protein expression of hnRNP C and its increase subsequently induce the translation of p(27) mRNA, which trigger the inhibition of cell growth via p(27)-regulated cell cycle arrest in YD-10(B) cells. | Celecoxib | heterogeneous nuclear ribonucleoprotein C | Homo sapiens |