Title : Estrogen suppression of erbB2 expression is associated with increased growth rate of ZR-75-1 human breast cancer cells in vitro and in nude mice.

Pub. Date : 1991 Oct 21

PMID : 1680817






2 Functional Relationships(s)
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1 The anti-estrogens toremifene and tamoxifen inhibited estrogen induction of pS2 expression, down-regulation of erbB2 expression and proliferation of the ZR-75-I cells in a concentration-dependent manner. Toremifene taste 2 receptor member 64 pseudogene Homo sapiens
2 Concomitant administration of toremifene or tamoxifen increased erbB2 mRNA and abolished pS2 mRNA. Toremifene taste 2 receptor member 64 pseudogene Homo sapiens