Title : Oxidative DNA damage induced by hair dye components ortho-phenylenediamines and the enhancement by superoxide dismutase.

Pub. Date : 2006 Sep 5

PMID : 16798066






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 o-PD and Cl-PD caused piperidine-labile and formamidopyrimidine-DNA glycosylase-sensitive lesions at cytosine and guanine residues respectively in the 5"-ACG-3" sequence, complementary to codon 273, a well-known hotspot of the human p53 tumor suppressor gene. formamidopyrimidine tumor protein p53 Homo sapiens