Pub. Date : 2006 Jun-Jul
PMID : 16775295
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The present study examined whether delayed vasospasm is associated with elevations in 20-HETE in CSF in the dual hemorrhage model of SAH in dogs and if blockade of the synthesis of 20-HETE with N-(3-chloro-4-morpholin-4-yl)phenyl-N"-hydroxyimido formamide (TS-011) can reverse delayed vasospasm in this model. | 20-hydroxy-5,8,11,14-eicosatetraenoic acid | colony stimulating factor 2 | Canis lupus familiaris |
| 2 | CONCLUSIONS: These results indicate that the development of delayed vasospasm in dogs is associated with an increase in 20-HETE levels in CSF, and acute blockade of the synthesis of 20-HETE with TS-011 reverses delayed vasospasm in this model. | 20-hydroxy-5,8,11,14-eicosatetraenoic acid | colony stimulating factor 2 | Canis lupus familiaris |