Title : Effect of Zn2+ on DNA recognition and stability of the p53 DNA-binding domain.

Pub. Date : 2006 Jun 20

PMID : 16768444






3 Functional Relationships(s)
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1 Effect of Zn2+ on DNA recognition and stability of the p53 DNA-binding domain. Zinc tumor protein p53 Homo sapiens
2 We have carried out molecular dynamics simulations to investigate the influence of Zn2+ on the p53 DNA recognition and the stability of the DBD. Zinc tumor protein p53 Homo sapiens
3 Our results suggest that L2 may be a frustrated and highly flexible element and play an important role in aggregation of Zn-free p53. Zinc tumor protein p53 Homo sapiens