Title : Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase kappa.

Pub. Date : 2006 Jul 28

PMID : 16751196






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Comparisons are made with similar studies done with human pols eta and iota; pol kappa is the most resistant to N(2)-bulk and the most quantitatively efficient of these in catalyzing dCTP incorporation opposite bulky guanine N(2)-adducts, particularly the largest (N(2)-BPG). Nitrogen DNA polymerase lambda Homo sapiens