Title : Geldanamycin treatment reduces neovascularization in a mouse model of retinopathy of prematurity.

Pub. Date : 2007 Feb

PMID : 16741710






1 Functional Relationships(s)
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1 BACKGROUND: The benzoquinoid antibiotic 17-allylaminogeldanamycin (17-AAG) inhibits the Ras/Raf/MEK and PI3-Kinase signaling pathways and down-regulates vascular endothelial factor expression. tanespimycin N-methylpurine-DNA glycosylase Mus musculus