Pub. Date : 2006 Nov
PMID : 16739126
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These data suggest that the direct inhibition of p53 functional activation is one of the mechanisms through which arsenite interferes with p53 function, and thus may be a significant mechanism for the co-carcinogenic effects of arsenite. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 2 | Arsenite inhibits p53 phosphorylation, DNA binding activity, and p53 target gene p21 expression in mouse epidermal JB6 cells. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 3 | Arsenite inhibits p53 phosphorylation, DNA binding activity, and p53 target gene p21 expression in mouse epidermal JB6 cells. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 4 | Arsenite may function as a co-carcinogen, acting by inhibiting repair of carcinogen-induced DNA damage mediated by p53 and p21, a p53 target gene. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 5 | Arsenite may function as a co-carcinogen, acting by inhibiting repair of carcinogen-induced DNA damage mediated by p53 and p21, a p53 target gene. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 6 | Our results indicated that arsenite suppressed UVB-induced p53 phosphorylation and p53 DNA binding activity. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 7 | Our results indicated that arsenite suppressed UVB-induced p53 phosphorylation and p53 DNA binding activity. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 8 | Arsenite also inhibited casein kinase 2 (CK2) activity and decreased p53-regulated p21 protein expression. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 9 | These data suggest that the direct inhibition of p53 functional activation is one of the mechanisms through which arsenite interferes with p53 function, and thus may be a significant mechanism for the co-carcinogenic effects of arsenite. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 10 | These data suggest that the direct inhibition of p53 functional activation is one of the mechanisms through which arsenite interferes with p53 function, and thus may be a significant mechanism for the co-carcinogenic effects of arsenite. | arsenite | transformation related protein 53, pseudogene | Mus musculus |
| 11 | These data suggest that the direct inhibition of p53 functional activation is one of the mechanisms through which arsenite interferes with p53 function, and thus may be a significant mechanism for the co-carcinogenic effects of arsenite. | arsenite | transformation related protein 53, pseudogene | Mus musculus |