Title : Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus.

Pub. Date : 2006 May 30

PMID : 16714379






2 Functional Relationships(s)
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1 Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Poly C interferon induced with helicase C domain 1 Mus musculus
2 Both RIG-I and mda-5 can bind polyriboinosinic:polyribocytidylic acid (polyI:C), the synthetic analog of viral dsRNA, and mediate type I IFN responses to polyI:C and multiple RNA viruses in vitro. Poly C interferon induced with helicase C domain 1 Mus musculus