Pub. Date : 2006 Sep
PMID : 16714086
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Attenuation of capsaicin-evoked mechanical allodynia by peripheral neuropeptide Y Y1 receptors. | Capsaicin | neuropeptide Y | Rattus norvegicus |
| 2 | In particular, previous studies have demonstrated that the Y1 subtype of NPY receptors inhibits nociceptive transmission from capsaicin-sensitive terminals in the dorsal horn of the spinal cord. | Capsaicin | neuropeptide Y | Rattus norvegicus |
| 3 | Treatment with the Y1 agonist [Leu31,Pro34]-NPY (0.5, 1, or 10 nmol) significantly inhibited capsaicin-evoked mechanical allodynia in a dose-dependent manner. | Capsaicin | neuropeptide Y | Rattus norvegicus |
| 4 | In isolated skin, application of [Leu31,Pro34]-NPY (300 nM) significantly inhibited capsaicin-evoked CGRP release. | Capsaicin | neuropeptide Y | Rattus norvegicus |