Title : Phosphorylation of JAK2 at serine 523: a negative regulator of JAK2 that is stimulated by growth hormone and epidermal growth factor.

Pub. Date : 2006 Jun

PMID : 16705159






1 Functional Relationships(s)
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1 When Ser523 in JAK2 was mutated, JAK2 kinase activity as well as GH-dependent tyrosyl phosphorylation of JAK2 and Stat5 was enhanced, suggesting that phosphorylation of Ser523 inhibits JAK2 kinase activity. cyclo(tyrosyl-tyrosyl) growth hormone 1 Homo sapiens