Title : Cumulative mutations affecting sterol biosynthesis in the yeast Saccharomyces cerevisiae result in synthetic lethality that is suppressed by alterations in sphingolipid profiles.

Pub. Date : 2006 Aug

PMID : 16702413






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 UPC2 and ECM22 belong to a Zn(2)-Cys(6) family of fungal transcription factors and have been implicated in the regulation of sterol synthesis in Saccharomyces cerevisiae and Candida albicans. Sterols Upc2p Saccharomyces cerevisiae S288C