Title : Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.

Pub. Date : 2006 May 1

PMID : 16651436






2 Functional Relationships(s)
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1 As an alternative approach to using P-gp inhibitors, we characterize a thiosemicarbazone derivative (NSC73306) identified in a generic screen as a compound that exploits, rather than suppresses, P-gp function to induce cytotoxicity. Thiosemicarbazones phosphoglycolate phosphatase Homo sapiens
2 As an alternative approach to using P-gp inhibitors, we characterize a thiosemicarbazone derivative (NSC73306) identified in a generic screen as a compound that exploits, rather than suppresses, P-gp function to induce cytotoxicity. Thiosemicarbazones phosphoglycolate phosphatase Homo sapiens