Title : Microwave-enhanced nucleophilic fluorination in the synthesis of fluoropyridyl derivatives of [3,2-c]pyrazolo-corticosteroids, potential glucocorticoid receptor-mediated imaging agents.

Pub. Date : 2006 Jul 1

PMID : 16644222






1 Functional Relationships(s)
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1 They are thus considered to be excellent candidates for PET imaging of GR containing tissues when labeled with fluorine-18 (t(1/2)=110 min). Fluorine-18 nuclear receptor subfamily 3 group C member 1 Homo sapiens