Title : [Effect of cyclosporin A on the production of IFN-gamma by murine splenocytes].

Pub. Date : 2006 May

PMID : 16643797






3 Functional Relationships(s)
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1 [Effect of cyclosporin A on the production of IFN-gamma by murine splenocytes]. Cyclosporine interferon gamma Mus musculus
2 AIM: To explore the effect of cyclosporine A (CsA) on the production of IFN-gamma by murine splenocytes after stimulation with different reagents. Cyclosporine interferon gamma Mus musculus
3 RESULTS: The mouse splenocytes stimulated with anti-CD3 mAb, anti-CD3 mAb + anti-CD28 mAb or anti-CD3 mAb + IL-12 could produce high level of IFN-gamma, but CsA inhibited INF-gamma production in a dose-dependent manner. Cyclosporine interferon gamma Mus musculus