Title : The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro.

Pub. Date : 2006 Jun

PMID : 16628188






1 Functional Relationships(s)
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1 The mechanism of cell killing was via PTL-induced generation of reactive oxygen species, resulting in turn in a proapoptotic Bax conformational change, release of mitochondrial cytochrome c and caspase activation. parthenolide cytochrome c, somatic Homo sapiens