Title : GRO-alpha regulation in airway smooth muscle by IL-1beta and TNF-alpha: role of NF-kappaB and MAP kinases.

Pub. Date : 2006 Jul

PMID : 16617094






3 Functional Relationships(s)
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1 ASMC were cultured from human airways, grown to confluence, and exposed to cytokines IL-1beta and TNF-alpha after growth arrest. asmc interleukin 1 beta Homo sapiens
2 Supernatants from IL-1beta-stimulated ASMC were chemotactic for neutrophils; this effect was inhibited by anti-GRO-alpha blocking antibody. asmc interleukin 1 beta Homo sapiens
3 IL-1beta- and TNF-alpha-stimulated expression of GRO-alpha from ASMC is regulated by independent pathways involving NF-kappaB activation and ERK and JNK pathways. asmc interleukin 1 beta Homo sapiens