Title : Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22.

Pub. Date : 2006 Jun

PMID : 16614259






1 Functional Relationships(s)
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1 Chemotactic responses of CEM and human Th2 cells to CCL17 and CCL22 were similarly abrogated by inhibition of PLC and inhibition of novel, Ca2+-independent/diacylglycerol-dependent protein kinase C (PKC) isoforms. 2-chloroethyl methyl sulfide C-C motif chemokine ligand 22 Homo sapiens