Pub. Date : 2006
PMID : 16610357
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | During GR-hsp90 heterocomplex assembly, the hydrophobic ligand-binding cleft is opened to access by steroid, and subsequent binding of steroid within the cleft triggers a transformation of the receptor such that it engages in more dynamic cycles of assembly/disassembly with hsp90 that are required for rapid dynein-dependent translocation to the nucleus. | Steroids | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
2 | During GR-hsp90 heterocomplex assembly, the hydrophobic ligand-binding cleft is opened to access by steroid, and subsequent binding of steroid within the cleft triggers a transformation of the receptor such that it engages in more dynamic cycles of assembly/disassembly with hsp90 that are required for rapid dynein-dependent translocation to the nucleus. | Steroids | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
3 | During GR-hsp90 heterocomplex assembly, the hydrophobic ligand-binding cleft is opened to access by steroid, and subsequent binding of steroid within the cleft triggers a transformation of the receptor such that it engages in more dynamic cycles of assembly/disassembly with hsp90 that are required for rapid dynein-dependent translocation to the nucleus. | Steroids | heat shock protein 90 alpha family class A member 1 | Homo sapiens |