Title : Carcinogenic pollutants o-nitroanisole and o-anisidine are substrates and inducers of cytochromes P450.

Pub. Date : 2005 Dec

PMID : 16601807






1 Functional Relationships(s)
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1 Using purified CYP enzymes, reconstituted with NADPH: CYP reductase, rabbit CYP2E1 was the most efficient enzyme oxidizing o-anisidine, but the ability of CYP1A1, 1A2, 2B2, 2B4 and 3A6 to participate in o-anisidine oxidation was also proved. NADP cytochrome P450 2E1 Oryctolagus cuniculus