Title : Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- mice.

Pub. Date : 2006 Apr 1

PMID : 16585156






1 Functional Relationships(s)
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1 Here, we show that loss of Pten in the mouse endometrium activates Akt and results in increased phosphorylation of estrogen receptor alpha (ERalpha) on Ser(167). Serine phosphatase and tensin homolog Mus musculus