Title : Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization.

Pub. Date : 2006 Apr

PMID : 16581796






1 Functional Relationships(s)
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1 Here, we show that AP2, a clathrin adaptor, binds directly to a tyrosine-based motif in the cytoplasmic tail of PAR1 and is essential for constitutive receptor internalization and cellular recovery of thrombin signaling. Tyrosine transcription factor AP-2 alpha Homo sapiens