Title : Inhibition of erythropoietin production by phorbol ester is associated with down-regulation of protein kinase C-alpha isoenzyme in hepatoma cells.

Pub. Date : 1991 Sep 30

PMID : 1656952






2 Functional Relationships(s)
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1 Treatment with phorbol 12-myristate 13-acetate (PMA) for 24 h dose-dependently inhibited Epo formation, thus suggesting that down-regulation of PKC might be responsible for this inhibition. Tetradecanoylphorbol Acetate erythropoietin Homo sapiens
2 Treatment with phorbol 12-myristate 13-acetate (PMA) for 24 h dose-dependently inhibited Epo formation, thus suggesting that down-regulation of PKC might be responsible for this inhibition. Tetradecanoylphorbol Acetate erythropoietin Homo sapiens