Title : A study of human erythrocyte acetylcholinesterase inhibition by chlorpromazine.

Pub. Date : 1991 Sep 1

PMID : 1654884






2 Functional Relationships(s)
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1 Membrane-bound acetylcholinesterase (AChE) from the human erythrocyte is inhibited by chlorpromazine (CPZ) in a concentration range within this amphiphilic drug has been demonstrated to interact with erythrocyte membranes, causing a large spectrum of physical and structural effects; membrane solubilization with 0.5% Triton X-100 results in a complete loss of CPZ inhibitory potency. Octoxynol acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Membrane-bound acetylcholinesterase (AChE) from the human erythrocyte is inhibited by chlorpromazine (CPZ) in a concentration range within this amphiphilic drug has been demonstrated to interact with erythrocyte membranes, causing a large spectrum of physical and structural effects; membrane solubilization with 0.5% Triton X-100 results in a complete loss of CPZ inhibitory potency. Octoxynol acetylcholinesterase (Cartwright blood group) Homo sapiens