Title : Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis.

Pub. Date : 2006 Mar

PMID : 16546966






2 Functional Relationships(s)
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Protein Name
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1 Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis. benzoquinone ansamycin heat shock protein 90 alpha family class A member 1 Homo sapiens
2 The benzoquinone ansamycin Hsp90 inhibitors geldanamycin and/or its derivatives 17-allylamino-17-demethoxygeldanamycin (17-AAG) and 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibited production of vascular endothelial growth factor (VEGF)-A by tumor cells and blocked proliferative responses of human endothelial cells at nanomolar concentrations. benzoquinone ansamycin heat shock protein 90 alpha family class A member 1 Homo sapiens