Title : Inhibition of the phosphatidylinositol 3-kinase/Akt pathway sensitizes MDA-MB468 human breast cancer cells to cerulenin-induced apoptosis.

Pub. Date : 2006 Mar

PMID : 16546963






1 Functional Relationships(s)
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1 Interestingly, the nonspecific caspase inhibitor, z-VAD-FMK, inhibited the down-regulation of Akt, XIAP, and cIAP-1 in cerulenin- and LY294002-treated cells. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone AKT serine/threonine kinase 1 Homo sapiens