Pub. Date : 2006 Mar
PMID : 16544946
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Detection of DNA adducts derived from the reactive metabolite of furan, cis-2-butene-1,4-dial. | furan | suppressor of cytokine signaling 2 | Homo sapiens |
| 2 | Furan undergoes oxidation by cytochrome P450 to cis-2-butene-1,4-dial, which is thought to mediate furan"s toxic effects. | furan | suppressor of cytokine signaling 2 | Homo sapiens |
| 3 | Furan undergoes oxidation by cytochrome P450 to cis-2-butene-1,4-dial, which is thought to mediate furan"s toxic effects. | furan | suppressor of cytokine signaling 2 | Homo sapiens |
| 4 | To determine the importance of DNA alkylation in furan-induced carcinogenesis, we developed an assay for the detection of cis-2-butene-1,4-dial-derived DNA adducts. | furan | suppressor of cytokine signaling 2 | Homo sapiens |